![β-Amyrin synthase from Euphorbia tirucalli. Steric bulk, not the π-electrons of Phe, at position 474 has a key role in affording the correct folding of the substrate to complete the normal polycyclization cascade]()
β-Amyrin synthase from Euphorbia tirucalli. Steric bulk, not the π-electrons of Phe, at position 474 has a key role in affording the correct folding of the substrate to complete the normal polycyclization cascadeIto, Ryousuke; Masukawa, Yukari; Nakada, Chika; Amari, Kanako; Nakano, Chiaki; Hoshino, Tsutomu · Organic & Biomolecular Chemistry · 2014