Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450

C. Nicholas Hodge; Paul E. Aldrich; Lee T. Bacheler; Chong-Hwan Chang; Charles J. Eyermann; Sena Garber; Mary Grubb; David A. Jackson; Prabharkar K. Jadhav; Bruce Korant; Patrick Y.S. Lam; Michael B. Maurin; James L. Meek; Michael J. Otto; Marlene M. Rayner; Carol Reid; Thomas R. Sharpe; Linyee Shum; Dean L. Winslow; Susan Erickson-Viitanen

作者C. Nicholas Hodge; Paul E. Aldrich; Lee T. Bacheler; Chong-Hwan Chang; Charles J. Eyermann; Sena Garber; Mary Grubb; David A. Jackson; Prabharkar K. Jadhav; Bruce Korant; Patrick Y.S. Lam; Michael B. Maurin; James L. Meek; Michael J. Otto; Marlene M. Rayner; Carol Reid; Thomas R. Sharpe; Linyee Shum; Dean L. Winslow; Susan Erickson-Viitanen
卷第3卷
期第4期
印刷ISSN1074-5521
文件大小2920.32KB
发表时间1996
DOI10.1016/s1074-5521(96)90110-6
页码301-314

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Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450