Potentiating AZT activation: structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants’ improved kinetics with the HIV prodrug metabolite AZTMP
Nils Ostermann; Arnon Lavie; Sreekanta Padiyar; Ralf Brundiers; Thomas Veit; Jochen Reinstein; Roger S Goody; Manfred Konrad; Ilme Schlichting
- 作者Nils Ostermann; Arnon Lavie; Sreekanta Padiyar; Ralf Brundiers; Thomas Veit; Jochen Reinstein; Roger S Goody; Manfred Konrad; Ilme Schlichting
- 卷第304卷
- 期第1期
- 印刷ISSN0022-2836
- 电子ISSN1089-8638
- 文件大小429.11KB
- 发表时间2000
- DOI10.1006/jmbi.2000.4175