海量图书期刊资源,随时随地畅享阅读乐趣
Statistical Evaluation of Clinical Trial Design for a Population Pharmacokinetic Study —A Case Study—Nakade, Susumu; Nishibori, Atsushi; Okamoto, Hiroyuki; Higuchi, Shun · Drug Metabolism and Pharmacokinetics · 2004
A Two-Part Mixture Model for Longitudinal Adverse Event Severity DataKenneth G. Kowalski; Lynn McFadyen; Matthew M. Hutmacher; Bill Frame; Raymond Miller · 2003
Efficient Screening of Covariates in Population Models Using Wald's Approximation to the Likelihood Ratio TestKenneth G. Kowalski; Matthew M. Hutmacher · 2001
Collapsing Mechanistic Models: An Application to Dose Selection for Proof of Concept of a Selective Irreversible AntagonistMatthew M. Hutmacher; Debu Mukherjee; Kenneth G. Kowalski; David C. Jordan · 2005
Exposure-response modeling using latent variables for the efficacy of a JAK3 inhibitor administered to rheumatoid arthritis patientsMatthew M. Hutmacher; Sriram Krishnaswami; Kenneth G. Kowalski · 2008