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Acylguanidine inhibitors of β-secretase: Optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets

Acylguanidine inhibitors of β-secretase: Optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets

Derek C. Cole; Joseph R. Stock; Rajiv Chopra; Rebecca Cowling; John W. Ellingboe; Kristi Y. Fan; Boyd L. Harrison; Yun Hu; Steve Jacobsen; Lee D. Jennings; Guixian Jin; Peter A. Lohse; Michael S. Malamas; Eric S. Manas; William J. Moore; Mary-Margaret O’Donnell; Andrea M. Olland; Albert J. Robichaud; Kristine Svenson; JunJun Wu; Eric Wagner; Jonathan Bard
  • 作者Derek C. Cole; Joseph R. Stock; Rajiv Chopra; Rebecca Cowling; John W. Ellingboe; Kristi Y. Fan; Boyd L. Harrison; Yun Hu; Steve Jacobsen; Lee D. Jennings; Guixian Jin; Peter A. Lohse; Michael S. Malamas; Eric S. Manas; William J. Moore; Mary-Margaret O’Donnell; Andrea M. Olland; Albert J. Robichaud; Kristine Svenson; JunJun Wu; Eric Wagner; Jonathan Bard
  • 卷第18卷
  • 期第3期
  • 印刷ISSN0960-894X
  • 文件大小406.01KB
  • 发表时间2008
  • DOI10.1016/j.bmcl.2007.12.010
  • 页码1063-1066
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