Rational design of orally-active, pyrrolidine-based progesterone receptor partial agonists
- 作者Scott K. Thompson; David G. Washburn; James S. Frazee; Kevin P. Madauss; Tram H. Hoang; Leahann Lapinski; Eugene T. Grygielko; Lindsay E. Glace; Walter Trizna; Shawn P. Williams; Chaya Duraiswami; Jeffrey D. Bray; Nicholas J. Laping
- 卷第19卷
- 期第16期
- 印刷ISSN0960-894X
- 文件大小411.07KB
- 发表时间2009
- DOI10.1016/j.bmcl.2009.06.055
- 页码4777-4780
Nucleosides and nucleotides. 132. Synthesis and biological evaluations of ring-expanded oxetanocin analogues: Purine and pyrimidine analogues of 1,4-anhydro-2-deoxy-d-arabitol and 1,4-anhydro-2-deoxy-3-hydroxymethyl-d-arabitolAkio Kakefuda; Satoshi Shuto; Takemitsu Nagahata; Jun-ichi Seki; Takuma Sasaki; Akira Matsuda · 1994
Synthesis of 2-Acetyl-4-hydroxynaphtho[2,3-b]pyran-5,10-dione and the 4-Deoxy Analogue as Models for Comparative Biological Evaluations.Farouk Ameer; Robin G. F. Giles; Ivan R. Green; Victor I. Hugo; Samir Patel; Rene Pearce · 2004
Synthesis of 2‐Acetyl‐4‐hydroxynaphtho[2,3‐ <i>b</i> ]pyran‐5,10‐dione and the 4‐Deoxy Analogue as Models for Comparative Biological EvaluationsAmeer, Farouk; Giles, Robin G. F.; Green, Ivan R.; Hugo, Victor I.; Patel, Samir; Pearce, René · Synthetic Communications · 2004
Synthesis and evaluation of anti-HIV-1 activity of 3′-azido-3′-deoxy-2′-O,4′-C-methylene-linked bicyclic thymine nucleosidesOlsen, Anne G.; Rajwanshi, Vivek K.; Nielsen, Claus; Wengel, Jesper · Journal of the Chemical Society, Perkin Transactions 1 · 2000
ChemInform Abstract: Synthesis and Evaluation of anti-HIV-1 Activity of 3′-Azido-3′-deoxy-2′-O,4′-C-methylene-Linked Bicyclic Thymine Nucleosides.Anne G. Olsen; Vivek K. Rajwanshi; Claus Nielsen; Jesper Wengel · 2001
Stereoselective Synthesis and Biological Evaluations of Novel 3′-Deoxy-4′-azaribonucleosides as Inhibitors of Hepatitis C Virus RNA ReplicationChiacchio, Ugo; Borrello, Luisa; Crispino, Lia; Rescifina, Antonio; Merino, Pedro; Macchi, Beatrice; Balestrieri, Emanuela; Mastino, Antonio; Piperno, Anna; Romeo, Giovanni · Journal of Medicinal Chemistry · 2009
Synthesis and Biological Evaluation of (2-Hydroxyethyl) 2-Deoxy-α-D- <i>Threo</i> -Pyranoside 3,4,2′-Trisphosphate, A Mimic of the Second Messenger Inositol 1,4,5-TrisphosphateRoussel, Fabien; Hilly, Mauricette; Chrétien, Françoise; Mauger, Jean-Pierre; Chapleur, Yves · Journal of Carbohydrate Chemistry · 1999