Whole-Molecule Antibody Engineering: Generation of a High-Affinity Anti-IL-6 Antibody with Extended Pharmacokinetics

Donna K. Finch; Matthew A. Sleeman; Jacques Moisan; Franco Ferraro; Sara Botterell; Jamie Campbell; Duncan Cochrane; Simon Cruwys; Elizabeth England; Steven Lane; Elizabeth Rendall; Monisha Sinha; Craig Walker; Gareth Rees; Michael A. Bowen; Amy Schneider; Meina Liang; Raffaella Faggioni; Michael Fung; Philip R. Mallinder; Trevor Wilkinson; Roland Kolbeck; Tristan Vaughan; David C. Lowe

作者Donna K. Finch; Matthew A. Sleeman; Jacques Moisan; Franco Ferraro; Sara Botterell; Jamie Campbell; Duncan Cochrane; Simon Cruwys; Elizabeth England; Steven Lane; Elizabeth Rendall; Monisha Sinha; Craig Walker; Gareth Rees; Michael A. Bowen; Amy Schneider; Meina Liang; Raffaella Faggioni; Michael Fung; Philip R. Mallinder; Trevor Wilkinson; Roland Kolbeck; Tristan Vaughan; David C. Lowe
卷第411卷
期第4期
印刷ISSN0022-2836
电子ISSN1089-8638
文件大小912.19KB
发表时间2011
DOI10.1016/j.jmb.2011.06.031

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Whole-Molecule Antibody Engineering: Generation of a High-Affinity Anti-IL-6 Antibody with Extended Pharmacokinetics