Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy

Frankowski, Kevin J.; Hedrick, Michael P.; Gosalia, Palak; Li, Kelin; Shi, Shenghua; Whipple, David; Ghosh, Partha; Prisinzano, Thomas E.; Schoenen, Frank J.; Su, Ying; Vasile, S.; Sergienko, Eduard; Gray, Wilson; Hariharan, Santosh; Milan, Loribelle; Heynen-Genel, Susanne; Mangravita-Novo, Arianna; Vicchiarelli, Michael; Smith, Layton H.; Streicher, John M.; Caron, Marc G.; Barak, Lawrence S.; Bohn, Laura M.; Chung, Thomas D. Y.; Aubé, Jeffrey

期刊名称ACS Chemical Neuroscience
作者Frankowski, Kevin J.; Hedrick, Michael P.; Gosalia, Palak; Li, Kelin; Shi, Shenghua; Whipple, David; Ghosh, Partha; Prisinzano, Thomas E.; Schoenen, Frank J.; Su, Ying; Vasile, S.; Sergienko, Eduard; Gray, Wilson; Hariharan, Santosh; Milan, Loribelle; Heynen-Genel, Susanne; Mangravita-Novo, Arianna; Vicchiarelli, Michael; Smith, Layton H.; Streicher, John M.; Caron, Marc G.; Barak, Lawrence S.; Bohn, Laura M.; Chung, Thomas D. Y.; Aubé, Jeffrey
卷第3卷
期第3期
印刷ISSN1948-7193
电子ISSN1948-7193
文件大小3247.70KB
发表时间2012-03-21
DOI10.1021/cn200128x
页码221-236

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Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy