Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds
Oppelt, Angela; Kaschek, Daniel; Huppelschoten, Suzanna; Sison-Young, Rowena; Zhang, Fang; Buck-Wiese, Marie; Herrmann, Franziska; Malkusch, Sebastian; Krüger, Carmen L.; Meub, Mara; Merkt, Benjamin; Zimmermann, Lea; Schofield, Amy; Jones, Robert P.; Malik, Hassan; Schilling, Marcel; Heilemann, Mike; van de Water, Bob; Goldring, Christopher E.; Park, B. Kevin; Timmer, Jens; Klingmüller, Ursula
- 期刊名称npj Systems Biology and Applications
- 作者Oppelt, Angela; Kaschek, Daniel; Huppelschoten, Suzanna; Sison-Young, Rowena; Zhang, Fang; Buck-Wiese, Marie; Herrmann, Franziska; Malkusch, Sebastian; Krüger, Carmen L.; Meub, Mara; Merkt, Benjamin; Zimmermann, Lea; Schofield, Amy; Jones, Robert P.; Malik, Hassan; Schilling, Marcel; Heilemann, Mike; van de Water, Bob; Goldring, Christopher E.; Park, B. Kevin; Timmer, Jens; Klingmüller, Ursula
- 卷第4卷
- 期第1期
- 电子ISSN2056-7189
- 文件大小1849.80KB
- 发表时间2018-12
- DOI10.1038/s41540-018-0058-z