Reactive Intermediates and Bioactivation Pathways Characterization of Avitinib by LC-MS/MS: In vitro Metabolic Investigation
- 期刊名称Journal of Pharmaceutical and Biomedical Analysis
- 作者Attwa, Mohamed W.; Kadi, Adnan A.; Abdelhameed, Ali S.
- 印刷ISSN0731-7085
- 文件大小1046.47KB
- 发表时间2018-11
- DOI10.1016/j.jpba.2018.11.033
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A highly efficient and sensitive LC-MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability studyKadi, Adnan A.; Abdelhameed, Ali S.; Darwish, Hany W.; Attwa, Mohamed W.; Al-Shakliah, Nasser S. · Biomedical Chromatography · 2016
A simple liquid chromatography-tandem mass spectrometry method to accurately determine the novel third-generation EGFR-TKI naquotinib with its applicability to metabolic stability assessmentAlrabiah, Haitham; Kadi, Adnan A.; Attwa, Mohamed W.; Abdelhameed, Ali S. · RSC Advances · 2019
Phase I metabolic profiling and unexpected reactive metabolites in human liver microsome incubations of X-376 using LC-MS/MS: bioactivation pathway elucidation and <i>in silico</i> toxicity studies of its metabolitesAttwa, Mohamed W.; Kadi, Adnan A.; Abdelhameed, Ali S. · RSC Advances · 2020
Editorial BoardJournal of Pharmaceutical and Biomedical Analysis · 2013
Editorial BoardJournal of Pharmaceutical and Biomedical Analysis · 2013
Editorial BoardJournal of Pharmaceutical and Biomedical Analysis · 2014
Editorial BoardJournal of Pharmaceutical and Biomedical Analysis · 2014
Editorial BoardJournal of Pharmaceutical and Biomedical Analysis · 2013
Editorial BoardJournal of Pharmaceutical and Biomedical Analysis · 2013
Editorial BoardJournal of Pharmaceutical and Biomedical Analysis · 2013
Editorial BoardJournal of Pharmaceutical and Biomedical Analysis · 2014