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Potentiating AZT activation: structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants’ improved kinetics with the HIV prodrug metabolite AZTMPNils Ostermann; Arnon Lavie; Sreekanta Padiyar; Ralf Brundiers; Thomas Veit; Jochen Reinstein; Roger S Goody; Manfred Konrad; Ilme Schlichting · 2000