![Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the Heat Shock Factor 1 (HSF1) stress pathway and CDK9.]()
Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the Heat Shock Factor 1 (HSF1) stress pathway and CDK9.Rye, Carl; Chessum, Nicola; Lamont, Scott; Pike, Kurt Gordon; Faulder, Paul F.; Demeritt, Julie; Kemmitt, Paul D; Tucker, Julie; Zani, Lorenzo; Cheeseman, Matthew; Isaac, Rosie; Goodwin, Louise; Boros, Joanna; Raynaud, Florence; Hayes, Angela; Henley, Alan; de Billy, Emmanuel; Lynch, Chris; Sharp, Swee; te Poele, Robert; O Fee, Lisa; Foote, KM; Green, Stephen; Workman, Paul; Jones, Keith · Med. Chem. Commun. · 2016