![Enantiomers of HA-966 (3-Amino-1-Hydroxypyrrolid-2-One) Exhibit Distinct Central Nervous System Effects: (+)-HA-966 is a Selective Glycine/N- Methyl-D-Aspartate Receptor Antagonist, But (-)-HA-966 is a Potent γ-Butyrolactone-Like Sedative]()
Enantiomers of HA-966 (3-Amino-1-Hydroxypyrrolid-2-One) Exhibit Distinct Central Nervous System Effects: (+)-HA-966 is a Selective Glycine/N- Methyl-D-Aspartate Receptor Antagonist, But (-)-HA-966 is a Potent γ-Butyrolactone-Like SedativeL. Singh, A. E. Donald, A. C. Foster, P. H. Hutson, L. L. Iversen, S. D. Iversen, J. A. Kemp, P. D. Leeson, G. R. Marshall, R. J. Oles, T. Priestley, L. Thorn, M. D. Tricklebank, C. A. Vass and B. J. Williams · Proceedings of the National Academy of Sciences of the United States of America · 1990